Some products that may interact with this drug include phosphate binders, antacids, laxatives, and other vitamins as they may contain calcium and phosphorus.

The recommended daily amount of vitamin D3 is 400 international units (IU) for children up to age 12 months, 600 IU for ages 1 to 70 years, and 800 IU for people over 70 years.

Vitamin D is lightly safe during pregnancy and breastfeeding when used in daily amounts below 4000 units. Do not use higher doses unless instructed by your health care provider.

In general, no significant adverse health effects on humans. Occasionally individuals experience mild side effects such as weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, and vomiting. This holds for all forms of Vitamin D3.

Generally, men and women who have low levels and to get an adequate level of Vitamin D3, calcium, and phosphorous can take this supplement.